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      Committee Composition

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      Audit Committee Compensation Committee Nominating and Corporate Governance Committee
      Sean P. Bohen, M.D., Ph.D.
      Cindy Butitta Audit Committee Compensation Committee
      Ian Clark Compensation Committee
      Cyrus Harmon, Ph.D.
      Sandra J. Horning, M.D., FACP, FASCO
      Gorjan Hrustanovic, Ph.D. Nominating and Corporate Governance Committee
      Yi Larson Nominating and Corporate Governance Committee
      Andy Rappaport Audit Committee Compensation Committee
      Graham Walmsley, M.D., Ph.D. Audit Committee Nominating and Corporate Governance Committee
      = Chairperson = Member = Chairman of the Board
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